What’s kisspeptin-10? : r/Testosterone. I’ve briefly looked up some things about kisspeptin-10, and from what I found people were constantly taking about it when there was a brief ban on HCG as a good and affordable substitute, and then people stopped talking about it out of no where. There weren’t any updates about how well it works or ...administration of gene product, drug-induced reactivation . ... Kisspeptins are four peptides, namely kisspetin-10, kisspeptin-13, kisspeptin-14 and kisspeptin-54 (or metastin), which are the ...1MCG per KG body weight, SQ for weekly dose (5mL) / 6-10 Week Supply: 5-Amino-1MQ: Weight Loss: 50mg daily capsule / 20 day supply: ARA-290 Inj: Nootropic: 6mg/mL SQ (4mL) / 4 week supply: BPC-157: ... Kisspeptin-10. Kisspeptin has recently emerged as a central regulator of gonadotropin function playing key role in puberty and reproductive ...This treatment is sometimes stretched out as far as 2 weeks for maximum effectiveness. To boost mental energy and avoid fatigue, 2-3 drops through each nasal passage 3 times during the morning for 3–5 days is the typical starting dosage prescription. The optimal daily amount of intake is between 400–900 mcg/day.Researchers from Imperial College London in the United Kingdom say the hormone kisspeptin could be used to treat HSDD. Scientists found that kisspeptin helps improve sexual brain processing ...Gonadorelin may work with TRT—producing endogenous LH and FSH—if you add a SERM. But it's not clear if even daily injections would be enough. Kisspeptin is untested in this capacity, as far as I know. It's an interesting peptide, as its suppression in TRT could be detrimental to us, which may also be the case with gonadorelin/GnRH. For kisspeptin alone to stimulate production of ...If you think that scandalous, mean-spirited or downright bizarre final wills are only things you see in crazy movies, then think again. It turns out that real people who want to make a lasting impression with their final wishes die all the ...Reddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog ... by Hisagi-kun. Kisspeptin-10 . Anyone know where to source this? Seems like a really promising compound. This thread is archived New comments cannot be posted and votes cannot be cast ... smaller doses of 125-250mcg per day for months or larger dose of 500-1000mcg for a ...The number following the name indicates the number of amino acids in the protein - for example, kisspeptin-10, the most effective version for raising LH levels and stimulating weight loss, is a sequence of 10 amino acids; Standard dose of .1-.2mL per injection, 2-3 times weekly; Some practitioners refer to kisspeptin as its original name ...Fact Checked This post has 16 references Dimitar Marinov, Ph.D. Last Updated September 19, 2023 Kisspeptin-10 Researchers are increasingly looking into the question of kisspeptin-10 dosage, with many looking for guidelines on how to use this peptide as an adjunct to testosterone replacement therapy.My clinic is out of hCG and I'm worried it's going to fuck up my levels not taking it.Overnight blood sampling was performed to determine the time profile of hormone release in 20 of the subjects treated with the two highest doses of kisspeptin-54 (6.4 or 12.8 nmol/kg; n = 10/dose). Peak levels of plasma kisspeptin were observed approximately one hour after injection and then fell to preinjection levels by 12 hours following ...Description. We are proud to offer kisspeptin-10 in a 20ml nasal spray with 50mcg per spray for a total of 20mg per bottle. Kisspeptin-10, also known as metastin, is a peptide hormone that has attracted significant attention for its role in the regulation of reproductive functions.Extensive research has been conducted to understand its mechanism of action, both in vitro and in vivo.Conclusions. Kisspeptin, a principal activator of GnRH neurons and the target of endocrine and metabolic cues, is a prerequisite for the onset of puberty and maintenance of normal reproductive function, as abnormal KISS1/GPR54 system has been reported in both animal models and patients with certain forms of infertility, e.g. Idiopathic Hypogonadotropic hypogonadism (IHH) and PCOS.Kisspeptin-10 Research. Research has shown that Kisspeptin-10 can increase the secretion of luteinizing hormone, follicle-stimulating hormone, and testosterone in men. It has also been found to stimulate gonadotropin release in women during the pre-ovulatory phase of the menstrual cycle. Moreover, Kisspeptin-10 has been shown to reactivate the ...Also what dosage should I do, I'm thinking 100mcg 3x a week. ... Ya I'm diving into the data right now because of another Reddit thread mentioning it. ... 175#, on pellet TRT, taking 100mcg of kisspeptin-10 daily in the AM and I intermittent fast 20/4. I have been taking that for 7 days and I feel phenomenal. Like every every day I best myself ...Kisspeptin 10 is much less potent than kiss54 which, unless you have seen a different study than me, is the one that can cause testicular degeneration in extremely high doses. Also, it’s completely impractical to do 20mcg every 2 hours.PCP and Endocrinologist don't want me to do TRT because of risk of cancer and heart problems. Whole genome sequencing reveals I have polymorphisms that make my aromatase malfunction. Rs4646 is one, this could be why I'm on 200mg per week and E2 is still in range. No AI.The plasma half-life of kisspeptin-54 was calculated to be 27.6 +/- 1.1 min. The mean metabolic clearance rate was 3.2 +/- 0.2 ml/kg x min, and the volume of distribution was 128.9 +/- 12.5 ml/kg. Conclusion: Elevation of plasma concentrations of kisspeptin in human males significantly increases circulating LH, FSH, and testosterone levels.1 4ChanRulez • 3 yr. ago Taking 150mcg EoD based on what other ppl on here r saying. It’s possible that Kisspeptin-10 is way better in that HCG was giving me a bunch of e2 sides, but right now I’m not so sure as I switched other things up. I’ll report back when I have a clearer idea on the testosterone subreddit. 2 VicariousPanda • 3 yr. ago Hey! Reddit; Jump to. Supplemental Material; Open Access Research Article. ... Fourth, the dose of KP‐10 (12.5 μg/kg per hour) infusion into mice is 9.6‐fold higher compared with its dose (1.3 μg/kg per hour ... Kisspeptin‐10 inhibits angiogenesis in human placental vessels ex vivo and endothelial cells in vitro.The ability of kisspeptin to affect LH secretion can be modulated by the ambient sex-steroid milieu in a time- and dose-dependent manner. J Clin Endocrinol Metab . 2017 Jun 1;102(6):2091-2099. doi: 10.1210/jc.2016-3952.Melanotan 2 Dosage Calculator. To achieve tanning of the skin, research suggests a melanotan 2 dosage range of 250mcg to 500mcg per day, injected subcutaneously. For testing on a first-time melanotan II subject, it is important to start with the lowest dose possible, before increasing as needed to achieve the desired outcome.Overall, kisspeptin plays a critical role in the regulation of the HPG axis and is essential for normal reproductive function. Pros & Cons of Synthetic Kisspeptin 10. Kisspeptin 10 is a synthetic form of the hormone kisspeptin that is used by researchers to study its effects on the reproductive system and metabolism.1 vote and 11 comments so far on RedditDose is 0.4 ml twice a week out of a 100 MCG/ML bottle. 1. InfiniteLlamaSoup • 2 yr. ago. 40mcg twice a week then. [deleted] • 2 yr. ago. Got it. Thanks. InfiniteLlamaSoup • 2 yr. …10 votes, 11 comments. 54K subscribers in the Peptides community. Everything about peptidesTirzepatide, or LY3298176, is a unimolecular dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is under study for its glycemic control and weight loss benefits [1, 2, 3].. Tirzepatide is based on the human GIP hormone and has a length of 39 amino acids. It includes a C20 fatty di-acid moiety that provides extended duration and ...Clinical trials with Kisspeptin-10 in healthy men show a dose-dependent and rapid increase in serum LH and testosterone levels. Kisspeptin-10 accomplishes this by increasing the pulsatile release of LH. ... Kisspeptin-10 was discovered about 20 years ago to suppress melanoma metastasis, a skin cancer, by approximately 95%, indicating …Dose alongside concurrent therapy Subcutaneous injection Cancer Kisspeptin-10 Injection 5mL at 100mcg/mL 0.1mL daily Patient preference Subcutaneous injection into abdomen LH increase KPV Topical 30ml TopiClick at 15mg/ml 0.5ml applied twice daily Patient preference Transdermal Cream PsoriasisOct 9, 2020 · Comparing Kisspeptin-10 and HCG. Kisspeptin peptides are critical in human reproductive physiology and are potential therapies for infertility. Kisspeptin-10 stimulates gonadotropin release in both male and females. While Kisspeptins are currently being studied in regards to the role of infertility, Kisspeptin-10 has been shown in many studies ...The ipamorelin/cjc1295 is a PIA to take because of the timing with meals. I may not continue it when I'm finished. The cost, the amount of time to see results, and the timing involved to take is just not worth it to me. Boring-Tell-1483 • 4 hr. ago.42 Therefore, the minimum dose level of kisspeptin-10 could not increase LH in acyclic goats. In ovariectomized ewes, injection of ovine kisspeptin (IV, 3 mg) increased serum LH concentration. 20 This dose was about 10-times more than the doses used in the present study. In addition, in anestrous season, administration of human kisspeptin 112 ...DidNotVote2020 • 4 mo. ago. HCG has a much longer half life. Kisspeptin might last less than 30 minutes. Kisspeptin might be better for getting fertility kickstarted initially, but all the research uses an IV infusion and if it is like gonadotropin the patient needs a pump to automatically release new infusions on a regular basis. It was ...A second dose of kisspeptin-54 at 10 h following the first improves oocyte yield in women at high risk of OHSS. WHAT IS KNOWN ALREADY. Kisspeptin acts at the hypothalamus to stimulate the release of an endogenous pool of GnRH from the hypothalamus. We have previously reported that a single dose of kisspeptin-54 results in an LH-surge of ~12 ...In this video, I share what happened after using kisspeptin-10 for 30 days. I have a lot more research and experiments to run with this peptide. I will keep ...Redirecting to /r/Testosterone/comments/gm1fyt/kisspeptin_10_dosage_amounts/fr5e70p/.In this video, I share what happened after using kisspeptin-10 for 30 days. I have a lot more research and experiments to run with this peptide. I will keep ...Kisspeptin-10, also sometimes referred to as KP-10, is the most effective and potent member of the Kisspeptin peptide family. Research suggests a significant role of Kisspeptin in earlier stages of reproductive development. Benefits of Kisspeptin-10. Kisspeptin-10 is a stimulator for gonadotropin-releasing hormone (GnRH) (5).INTRODUCTION. Kisspeptin (KP, also known as metastin) is one of a family of RFamide-related peptides that was originally found in the human placenta 1,2.The gene, KISS1, that encodes this peptide is first discovered in 1996 as a metastasis suppressor gene 3.The product of the Kiss1 gene is a 145 amino acid peptide from which shorter peptides (kisspeptin 54, 14, 13 and 10) are derived.This dose of kisspeptin-54 is higher than the dose required for maximal stimulation of gonadotrophin and testosterone release (Thompson et al., 2004; Navarro et al., 2005a,b; Patterson et al., 2006). Although the percentage of damaged seminiferous tubules varied between animals, there was qualitative evidence of tubule degeneration following ...The dose-response curves for human and canine KP10 are shown in Fig 2A and 2B, respectively. The EC50 of human and canine KP10 is 1.2 nM and 8 nM, respectively. ... The effects of kisspeptin agonist canine KP-10 and kisspeptin antagonist p271 on plasma LH concentrations during different stages of the estrous cycle and anestrus in the bitch ...Clinical researches about kisspeptin effects is conflicted by the two chief derivatives, kisspeptin -10 and -54, with different pharmacokinetic outlines and routes of administration. The variances between the effects of kisspeptin-10 and -54 are due that kisspeptin-10 has 6-fold shorter plasma half-life in comparison with kisspeptin-54 [18].Just checking in to see if you have any new info on Kisspeptin-10. I am on TRT and my Dr is recommending using K-10 as a replacement to HCG now that it can no longer be compounded by my pharmacy.Plasma FSH levels were not altered in any of the treatment groups. LH concentrations decreased at both 1 ng (P < 0.05) and 1 μg kisspeptin doses (P < 0.01), while levels at 10 pg dose did not differ significantly from those of controls.Plasma testosterone concentration was also significantly decreased at both 1 ng and 1 μg doses (P < 0.05; P < 0.01 respectively) as compared to control but no ...Hello i am currently on trt however, There is currently a problem with the availability of hcg in my country. I became interested in kisppeptin-10 to replace hcg, in theory it looks much better than hcg. Could someone share opinions about this peptide, and the dosage. #1 My Dr told me that their pharmacy can no longer compound HCG, but that he is going to start using Kisspeptin-10 as the alternative without increasing my monthly fee. He told me that Kisspeptin acts like GnRH and stimulates the Pituitary to release both LH and FSH.Based on our previous experience of kisspeptin infusions, a dose of 1 nmol/kg/h of kisspeptin-54 was selected so as to provide steady-state levels of circulating kisspeptin from 30 to 75 ... Jayasena CN, et al. The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. J Clin Endocrinol Metab. 2011;96(12 ...HCG VS Kisspeptin-10 VS Gonadorelin. Hello my fellow TRT peeps. My clinic just switched me from HCG to Kisspeptin and now Gonadorelin. I am a bit leary about the switch because of a lot of the things I am reading online when it comes down to which one is best. Looking for more info!Potential Benefits of Kisspeptin. Increases testosterone levels [1-5] Lowers the risk of heart disease [6-11] Boosts immunity [12-14] Helps lose weight [15-17] Prevents wrinkles and other signs of skin aging [18] Prevents cancer [19-26] Boosts brain power [27-29] Treats fertility disorders [30-35]Kisspeptin-10 should not be dosed too frequently, as research with other kisspeptins involving twice-daily dosage reports receptor desensitization. This can lead to the opposite effect and reduce testosterone levels . Here is a reference kisspeptin-10 dosing protocol based on the aforementioned studies and evidence-based considerations:Sermorelin + GHRP 6. Another good contender for the best peptide stack ever is the combination of Sermorelin and GHRP 6. For Sermorelin, its most known as being an analogue of growth hormone releasing hormone. It effects the release of growth hormone from the pituitary gland. By doing so, it aids with better fat burn, better endurance, and even ...I didn't see anything in the FAQ prohibiting asking this. I'm new here. The last 2 times I ordered Kisspeptin-10 was through Peptide Sciences. They …Peripheral administration of kisspeptin-10 also stimulates plasma LH and FSH in prepubertal and adult rats and LH in agonadal juvenile male monkeys (12, 13, 15, 16). ... This dose of kisspeptin-54 was chosen because it was the lowest infusion dose that maximally increased LH levels in male volunteers in study 1. Rates of saline infusion …precocious puberty [1,7,10]. The central role of kisspeptin in stimulating hypothalamic GnRH secretion is undisputed. Yet, the peripheral role of kisspeptin in tissues such as the testes is less well understood. The testes are essential for male reproduction through their two prime functions, namely spermatogenesis and steroidogenesis.Here are my protocols and labs. All labs were taken in the morning, and on off days, between days of taking Kissptin/HCG. *20mg ED Test *150iu EoD Kisspeptin *TT 1189 *FT 30.8 *E2 51 Feelings: Didn't really feel any difference from HCG. Maybe a little more "complete", but that very well could be me convincing myself that I should feel a change.Overnight blood sampling was performed to determine the time profile of hormone release in 20 of the subjects treated with the two highest doses of kisspeptin-54 (6.4 or 12.8 nmol/kg; n = 10/dose). Peak levels of plasma kisspeptin were observed approximately one hour after injection and then fell to preinjection levels by 12 hours following ...The company cant suggest a dosage as its meant to be for research only. This thread is archived New comments cannot be posted and votes cannot be castGonadorelin may work with TRT—producing endogenous LH and FSH—if you add a SERM. But it's not clear if even daily injections would be enough. Kisspeptin is untested in this capacity, as far as I know. It's an interesting peptide, as its suppression in TRT could be detrimental to us, which may also be the case with gonadorelin/GnRH. For kisspeptin alone to stimulate production of ...What is Kisspeptin-10 Peptide? Kisspeptin-10 peptide plays a part in controlling hormone secretion connected with reproduction. This research peptide has the ability to control testosterone levels and sexual drive and performance. Kisspeptin is a natural hormone that stimulates other reproductive hormones in the body. How a Kisspeptin-10 Dosage ...It is concluded that chronic intermittent administration of kisspeptin-10 has a dose-dependent degenerative effect on the plasma testosterone levels and Leydig cells ultrastructure in prepubertal male rats. ... We administered a range of kisspeptin-10 doses (1 μg, 1 ηg, and 10 ρg) intraperitoneally to prepubertal male Sprague-Dawley rats ...1 vote and 11 comments so far on RedditReddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog Careers Press. ... There are theories on the forum about kisspeptin as well. I wonder if this would help with PSSD symptoms too. comments sorted by Best Top New Controversial Q&A Add a Comment. ... i took my first dose of lexapro yesterday and ive lost all sex drive already.Real estate is often portrayed as a glamorous profession. Real estate agents, clients and colleagues have posted some hilarious stories on Reddit filled with all the juicy details about the most out-of-the-ordinary things they have experien...cough, stuffy nose; headache, tiredness, dizziness; or. pain, bruising, redness, itching, bleeding, numbness, or tingling where an injection was given. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In this study, the pattern of oocyte maturation significantly increased from 5 to 10 µg/ml and then decreased at 15 µg/ml. In vivo secretion of LH in response to KP administration was found to vary with dose, breed and physiological status of animal [13-15,27]. The action of KP on maturation of oocytes in vitro is different to that from in vivo.Week 1-3: Start GnRH SubQ injections, gradually increase dose and frequency to five per day @ 20 mcg per dose. 100 mcg total ED SubQ. Can also be taken as one SubQ injection ED. Week 4-end of TRT cycle (continued after the cycle is over for 4-6 weeks): Start Enclomiphene citrate @ 12.5 mg PO daily + 50 mcg kisspeptin-10 daily.In 6- and 10-month-old rats, ovaries infused with a low dose of kisspeptin had a fewer number of antral follicles, but an increased number of preovulatory follicles and corpora lutea. On the contrary, ovaries infused with P234 had an increased number of antral follicles and a decreased number of preovulatory follicles and corpora lutea.kisspeptin-54 is the one that really stimulates large LH/FSH secretion increases. yet to find a source though. kiss 10 is worthless. alpha fragment of HCG is more helpful. Kisspeptin is not incredibly effective either way — for most there is no LH increase. When you do use it, it builds up a tolerance after a few weeks.Kisspeptin-10, -14, and -54 have similar efficacy in vitro . However, we used kisspeptin-54 in our study because kisspeptin-54 is more efficacious than shorter kisspeptin fragments in vivo (11, 35). Subjects. ... The dose of kisspeptin-54 (0.4 nmol/kg) used in this study caused only a small increase in circulating gonadotropins in the dose ...The neuropeptide kisspeptin is now well-established as the master regulator of the mammalian reproductive axis. Beyond the hypothalamus, kisspeptin and its cognate receptor are also extensively distributed in extra-hypothalamic brain regions. An expanding pool of animal and human data demonstrates that kisspeptin sits within an extensive neuroanatomical and functional framework through which ...Bremelanotide: New Drug Approved for Treating Hypoactive Sexual Desire Disorder Ann Pharmacother. 2020 Jul;54(7):684-690. doi: 10.1177/1060028019899152. Epub 2020 Jan 1. Authors Danielle Mayer 1 , Sarah E Lynch 2 Affiliations 1 Thomas Jefferson University, Philadelphia, PA, USA. 2 ...#1 My Dr told me that their pharmacy can no longer compound HCG, but that he is going to start using Kisspeptin-10 as the alternative without increasing my monthly fee. He told me that Kisspeptin acts like GnRH and stimulates the Pituitary to release both LH and FSH.In my experience (simply anecdotal-and one, single personal account), there's no comparison. hCG was far superior; I had only positive results, no negative side effects from hCG. hCG-blood tests following ~4 & 12 wks. use indicated positive changes to LH, FSH, etc. Gonadorelin, the other hand, was the opposite: nothing but negative sides and ...1MCG per KG body weight, SQ for weekly dose (5mL) / 6-10 Week Supply: 5-Amino-1MQ: Weight Loss: 50mg daily capsule / 20 day supply: ARA-290 Inj: Nootropic: 6mg/mL SQ (4mL) / 4 week supply: BPC-157: ... Kisspeptin-10. Kisspeptin has recently emerged as a central regulator of gonadotropin function playing key role in puberty and reproductive ...Please contact the moderators of this subreddit if you have any questions or concerns. Kisspeptin-10 has a half-life of 4 minutes and kisspeptin-54 has a half-life of 28 minutes. Comparatively, hCG has a half-life of 24 hours (all times are approximate). Kisspeptin is effective while active but you'll need to inject throughout the day for it to ...Our previous results showed that kisspeptin-10 (Kp-10) injections via intraperitoneal (i.p.) once daily for three weeks notably promoted the egg laying rate in quails. In order to investigate the mechanism behind the effects of Kp-10 on enhancing the egg laying rate in birds, this study focused on t …May 15, 2021 · May 15, 2021. #2. It might help, but there's little information about this application. Because kisspeptin cannot be prescribed there's not going to be widespread use anytime soon. You can also go one hormone downstream and use gonadorelin. Royal Medical Center has offered some data showing that LH and FSH pulses are produced at larger doses. Description Certificate of Analysis High Performance Liquid Chromatography Mass Spectrometry Kisspeptin-10 Peptide. Kisspeptin-10 is a naturally occurring peptide protein that researcher suggest is encoded by the KISS1 gene (2).Kisspeptin is a product of the KISS1 gene, which is produced due to the cleavage of the original 145 amino acid peptide to a smaller peptide composed of 54 amino acids (6).10 votes, 11 comments. 54K subscribers in the Peptides community. Everything about peptidesThis review examines the physiological role of kisspeptin and the kisspeptin receptor in the control of gonadotrophin and gonadal steroid hormone secretion and the implications of these findings with respect to fertility. In addition, the potential therapeutic use of kisspeptin in the treatment of reproductive disorders will be examined.
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May 24, 2023 · Kisspeptin-10. Kisspeptin, controlled by the KISS1 gene, is a prospective regulator of the mammalian reproductive system. Kisspeptin-10, also sometimes referred to as KP-10, is the most effective and potent member of the Kisspeptin peptide family. Research suggests a significant role of Kisspeptin in earlier stages of reproductive development. Kisspeptin-10 (HCG Alternative): Benefits, Dosage, & Side Effects. Kisspeptin-10 is an excellent alternative to HCG and works well with testosterone, offering many benefits to …Reddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog Careers Press. ... Due to the lack of availability of HCG, my doctor is giving me a choice to switch to either Clomid , gonadorhelin, or kisspeptin, Clomid a pill other two are injections, gonadorhelin twice a week , kisspeptin every day injections.Although continuous kisspeptin administration does not immediately stimulate LH release in the postmenopausal state, estradiol appears to affect responsiveness to kisspeptin in a time- and dose-dependent manner. The mechanisms that underlie that modulation, and which neuronal populations are modulating the effects …So I’ve been researching about sexually enhancing peptides for a while and I’m considering taking kisspeptin-10 to increase FSH & LH to them produce more endogenous …Kisspeptin 10 is given as an injection into the upper arm or buttock. The usual dose is 10 units per day. Kisspeptin 10 is a medication that helps to regulate the body's natural production of the hormone kisspeptin. Kisspeptin is responsible for regulating puberty, fertility, and other reproductive functions.PT-141, also known as bremelanotide, is an FDA-approved treatment of hypoactive sexual desire disorder (HSDD) in women [ 1 ]. It is a modified synthetic derivative of alpha-melanocyte-stimulating hormone (α-MSH), a peptide of the melanocortin family that regulates skin pigmentation, feeding behavior, and sexual activity, among its other functions.When you purchase peptides online, Paradigm Peptides ships Monday through Friday within 48 hours of payment. If you buy peptides with an e-check, it takes 7-10 business days. Expedited shipping options are available. Please note that shipping rates will vary depending on your location and selected shipping method.Kisspeptin is a product of KISS1 gene that binds to a G-protein-coupled receptor (GPR54/KISS1R) stimulating the release of GnRH by hypothalamic neurons, leading to secretion of pituitary gonadotropins (LH and FSH) and sexual steroids, which in turn will act in the gonads to produce the gametes. Kisspeptin is being recognized as a crucial ...HCG is dosed in IU's, and dosage depends on how hard your cycle will have suppressed your natural testosterone. 250mg of Test Cyp a week might not even need a HCG dose at all, if you went the kitchen sink approach, you get the idea. 1.) Mild Cycle. HCG: 1000 - 2000 IU Every Day for the first 4 - 5 days. Enclomiphene: 12.5mg everyday, for ...Dec 1, 2011 · The highest plasma kisspeptin IR was observed after iv bolus injection of 10 nmol/kg kisspeptin-10 (mean AUC kisspeptin IR in women during follicular phase was 527 ± 108 h·pmol/liter, P < 0.001 vs. saline); this was lower when compared with kisspeptin IR after injection of the same dose of kisspeptin-10 to men, but this difference was not ... An intravenous bolus dose of 0.3 µg/kg (0.23 nmol/kg) of kisspeptin-10 was selected based on our recent dose–response study (George et al., 2011). At the end of this 6-h study period, a 100 µg bolus of GnRH was administered intravenously and four further samples obtained at 15-min intervals.Starting Kisspeptin on TRT. Let me doctor know my wife and I are starting the pregnancy process and are trying to get pregnant within the next year or so. I will be injecting my normal 0.3 ml of Test every other day. Levels hover between 600-800. Doctor has recommended 0.4 ml of Kisspeptin, twice per week.It is much different than hCG. Also, Gonadorelin given in large injections actually causes complete shutdown and sterility due to GnRH receptor desensitization on the pituitary. GnRH needs to be given in pulses every 120 minutes via a pump, not injected. Kisspeptin is the same thing, it can cause complete shutdown of the axis if given frequently. .
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